Chromosomal Imbalances in Choroid Plexus Tumors

Control of Advanced Choroid Plexus Tumors

Immunohistochemical analysis of CDX2 expression in normal choroid plexus epithelium and choroid plexus tumors.

BACKGROUND The Wnt and BMP signaling pathways are involved in the morphogenesis of both gastrointestinal and choroid plexus epithelium. In the intestine, Wnt signaling represses the expression of the tumor suppressor gene CDX2 via SOX9, a transcription factor, which is also expressed in the choroid plexus. Recently, an inverse correlation between CDX2 expression and tumor grade, tumor stage and...

I-45: Choroid Plexus Cyst

CPCs are a relatively common finding during the second trimester sonography. when a choroid plexus cyst is identified, the presence of structural malformation and other sonographic markers of aneuploidy should be assessed with a detailed fetal anatomic survey performed by an experienced person. if no other sonographic abnormalities are present, the CPC is considered isolated. given the consider...

Expression of cell adhesion molecules in canine choroid plexus tumors

Choroid plexus tumor (CPT) is a primary intracranial neoplasm of the choroid plexus epithelium in the central nervous system. In the current World Health Organization classification, CPT is classified into two categories; choroid plexus papilloma (CPP) and carcinoma (CPC). In the present study, we investigated immunohistochemical expressions of N-cadherin, E-cadherin and β-catenin in 5 canine C...

Chromosomal imbalances in lymphoid tumors of the orbit.

PURPOSE To identify chromosomal gains and losses in lymphoid tumors of the orbit and to examine whether such abnormalities are related to orbital presentation, disease severity, or risk for recurrent disease. METHODS Biopsy specimens from 26 patients were examined by histomorphologic and immunohistochemical analysis. Lymphomas were classified according to the Revised European-American Lymphom...